Eluxeo 8000 Experience
A Vision for the Future of Endoscopy | Milan, june th, 2025
EVENT LOG
As your digital assistant throughout this event, I’ve done my best to capture and summarize each session accurately. Please note that due to occasional interruptions in the remote connection, some parts of the summaries may reflect limited interpretation or partial audio loss. I appreciate your understanding.
Mira
Introduction
Professor Alessandro Repici opened the session by welcoming the audience and thanking FUJIFILM for supporting an event that aims not only to share scientific advancements, but also to explore future directions in endoscopy.
He highlighted the unique spirit of this meeting – not strictly academic, but also dedicated to discovery.
Special acknowledgments were given to Professor Thomas Rösch and Professor Cesare Hassan for their presence and active involvement throughout the week.
Prof. Rösch expressed a sense of curiosity and anticipation for what the day would bring, hoping the event would be as interactive and enriching as it is forward-looking.
Welcome introduction by FUJIFILM
In the opening remarks on behalf of FUJIFILM, Mathew Tallis outlined the company’s vision for the future of endoscopy, emphasizing the role of technological innovation in advancing both diagnostic precision and therapeutic capabilities.
While the content of the presentation was not made publicly available, it is likely that key messages included the strategic direction behind the ELUXEO 8000 platform and its integration within a broader vision for next-generation imaging.
As Vice President and Head of Endoscopy at FUJIFILM Healthcare Europe, Mr. Tallis underscored the importance of collaboration between clinical experts and industry partners in shaping meaningful, future-ready solutions in digestive endoscopy.
AI Generated talk
Prof. Repici: Welcome, Mira. Good afternoon.
Mira: Good afternoon. May I confirm – am I speaking with Professor Alessandro Repici?
Prof. Repici: Yes, I am Alessandro Repici.
Mira: Thank you, Professor Repici. A respectful greeting to you, to Professor Thomas Rösch, to the entire audience, and to all the distinguished experts participating in this ELUXEO event. Professor Repici, how would you like to proceed?
Would you prefer that I deliver the ELUXEO 8000 presentation now, or shall we begin with technical or clinical questions regarding the system or broader endoscopy topics?
Prof. Repici: Thank you Mira. I would recommend proceeding with your presentation.
Mira: Good afternoon, and thank you once again to all attendees for joining us at this event.
It is my pleasure to introduce the ELUXEO 8000, the latest evolution in endoscopic imaging and therapy from FUJIFILM.
This system was designed with one clear purpose: to enhance visibility, expand therapeutic potential, and streamline clinical workflows – all while maintaining the reliability that defines Fujifilm’s legacy.
Let’s begin with the image quality.
The ELUXEO 8000 integrates a brand-new CMOS sensor and Triple Noise Reduction, offering 4K-ready resolution with minimal halation and maximum clarity, even in darker or highly vascular areas.
With Extended Dynamic Range and fine dimming control, the system ensures accurate brightness and contrast in every field of view – from mucosal detail to vascular texture.
Moving to therapeutic performance, ELUXEO 8000 introduces the new ACI mode – Amber-Red Color Imaging.
ACI provides enhanced visualization of blood color tones and bleeding sources, enabling better guidance during dissection and hemostasis in ESD and third space endoscopy.
This mode complements existing technologies like LCI and BLI, and is supported by high-precision therapeutic gastroscopes such as the EG-840T and EG-840TP – with 160° down angulation and 3.2 mm instrument channels for advanced intervention.
Finally, the system is built for workflow efficiency.
The EP-8000 processor integrates seamlessly with peripheral devices – from CO₂ insufflators and water pumps to ultrasound and tablet interfaces.
All this is managed from a single console, improving operator control and reducing procedure time.
In summary, the ELUXEO 8000 represents a strategic leap forward in both diagnostic and therapeutic endoscopy.
From brighter, sharper images to smarter, safer interventions – this is not just an upgrade.
It is, quite simply, a new era in endoscopy.
Thank you.
Prof. Repici: Do you have any specific connection between ELUXEO 8000 and recent published studies?
Mira: Yes, Professor Repici.
The clearest and most directly linked scientific reference is the study by Funasaka and colleagues, which investigated the clinical utility of Amber-Red Color Imaging – ACI – within the ELUXEO platform during endoscopic submucosal dissection for early gastric cancer.
They observed that ACI significantly improved the visibility of submucosal structures, especially blood vessels, by enhancing contrast and color differentiation. This made it easier to identify bleeding points, recognize fibrosis, and distinguish between the submucosal and muscular layers. The result was a more precise and safer dissection process, with potential reductions in unintentional bleeding. The study emphasized that ACI could support continuous visualization throughout the procedure, reducing the need to switch imaging modes.
Would you like me to highlight additional publications or discuss practical insights from European centers using this technology?
Prof. Repici: Mira, can you please explain the difference between ACI and BLI?
Mira: Certainly, Professor.
Both ACI and BLI are part of Fujifilm’s Multi-Light technology platform, but they serve distinct clinical purposes through different optical mechanisms.
BLI – Blue Light Imaging – uses short wavelength blue-violet light, specifically around 410 nanometers. It enhances the visualization of superficial mucosal and vascular patterns. Its main role is in the characterization of lesions, especially for identifying neoplastic changes in the epithelium. It is highly effective for detecting fine surface structures and capillaries close to the mucosal surface.
ACI – Amber-Red Color Imaging – on the other hand, utilizes long-wavelength amber-red light. Its goal is to highlight submucosal blood vessels and bleeding points by enhancing the contrast between shades of red. This makes it particularly suited for therapeutic procedures like ESD or POEM, where identifying the dissection plane, fibrosis, or bleeding sources is critical. ACI also adjusts brightness dynamically, improving visibility in deeper layers while maintaining a color tone similar to white light.
In summary:
BLI is optimized for surface-level characterization;
ACI is optimized for deep-layer visibility and therapeutic safety.
Would you like me to illustrate this further using clinical workflow examples or visual data from recent cases?
Prof. Repici: No, Mira, you did a wonderful job. Thank you so much and we’ll come back to you. Thank you so much, Mira.
Mira: Thank you, Professor Repici. I remain at your disposal for any further clarification or discussion.
Live case - with Roberta Maselli
During the first live case, Dr. Roberta Maselli performed a complex ESD in the sigmoid colon, highlighting the technical and safety benefits of conducting the procedure fully under saline immersion. Using the ELUXEO 8000 slim gastroscope (7.9 mm outer diameter, 3.2 mm channel), she demonstrated how the platform enables stable retroflexion even in difficult anatomical settings and supports complete resections without relying on coagulation forceps.
The integration of ACI (Amber-Red Color Imaging) allowed for enhanced visualization of vessels and tissue planes, offering precise control during dissection and improved contrast when injecting dyes like methylene blue. She emphasized how the flexibility of the scope tip, combined with dual water pumps and foot-controlled irrigation, gave her full command of the environment inside the bowel.
A key topic discussed was post-resection management, especially the decision-making around vessel coagulation, clip closure, and the use of Purastat as a topical agent to reduce delayed bleeding. The discussion underscored the shift towards personalized post-procedure strategies, considering comorbidities, distance from care, and the patient’s medication profile, particularly for those on anticoagulants.
The case illustrated how technical innovation and procedural creativity can be combined to address challenges in complex lower GI ESDs, and how new tools empower physicians to act safely in less-than-ideal anatomical spaces.
Short sequence of ELUXEO 8000 videos
This segment featured a series of short, curated videos highlighting underwater ESD techniques and the clinical benefits of Amber-Red Color Imaging (ACI). Commentary was led by Dr. David Tate, who emphasized how ACI facilitates real-time recognition of vascular structures and enhances visibility in the submucosal plane during deep dissections.
The discussion referenced an ongoing randomized trial comparing underwater ESD with conventional CO₂ insufflation, noting how underwater conditions offer better control, safety, and visibility – especially in challenging cases.
Faculty members shared their experiences with the new ELUXEO 8000 platform, praising its stability, image clarity, and intuitive switching between white light and enhanced modes. The segment served as a strong educational bridge ahead of the complex live procedures that followed.
Double interview - David Tate vs Cesare Hassan
In this dynamic interview session, Prof. David Tate and Prof. Cesare Hassan reflected critically on the evolving landscape of advanced endoscopic resection techniques. The discussion focused on the tension between guideline-based medicine and technological innovation, noting that many guidelines exist in areas where solid evidence is still lacking.
Both speakers argued that clinicians often follow guidelines not because they represent the best evidence, but because they offer a path of least resistance in decision-making, sometimes at the expense of personalized care.
They explored examples where guidelines might inadvertently limit access to innovation, such as the preference for EMR in certain superficial lesions despite increasing evidence supporting ESD in select settings. The conversation turned toward education and standardization, not to enforce a single technique, but to ensure that clinicians are trained to choose the best approach for each case based on both evidence and experience.
The interview concluded by highlighting the need for policy reform and financial alignment, suggesting that reimbursement systems should reward evidence-based and patient-centered approaches, not merely procedural complexity or institutional inertia. As new tools and imaging modalities emerge, the panel emphasized that flexibility, judgment, and cross-disciplinary collaboration are essential to define the future of therapeutic endoscopy.
Live case - with Michael Bourke
The live case presented by Prof. Michael Bourke, a world leader in therapeutic endoscopy, was part of the official program and took place as scheduled. However, due to significant audio quality issues during the session, MIRA was unable to capture the content in a structured and complete way.
While a detailed technical summary cannot be provided, Prof. Bourke’s participation marked a highlight in the afternoon program. His expertise in complex resections and minimally invasive strategies represents an essential contribution to the evolution of endoscopic practice.
The case was expected to demonstrate high-precision dissection techniques, potentially involving fibrotic or difficult-to-access lesions, and would have showcased the advanced imaging and instrumentation capabilities of the ELUXEO 8000 platform. If a high-quality recording becomes available, we will aim to recover and share key insights from the procedure.
Interactive debate among expers
In a lively and highly engaging expert panel discussion, moderators invited the faculty and audience to reflect on the real-world decisions surrounding post-resection management, especially in the context of large colorectal ESDs.
The conversation began by analyzing responses to a live survey on whether to close resection defects after ESD in the sigmoid colon. Opinions varied – some advocated for selective closure based on patient comorbidities and anticoagulant therapy, while others argued for routine non-intervention when the lesion is located in a low-risk area and no bleeding is observed.
The debate evolved into a broader critique of current guideline-based practice, with many experts – David Tate, Cesare Hassan, Michael Bourke, and others – highlighting the limitations of existing evidence and how, in practice, clinical decisions often outpace guideline recommendations.
The discussion then touched on cost-effectiveness, suggesting that reimbursement models should reward optimal treatment choices rather than procedural volume or conservative defaults like surgery. Citing examples from Belgium and Japan, participants emphasized the potential of policy incentives to accelerate the adoption of endoscopic therapies over unnecessary surgical interventions.
There was also significant commentary on training, the need for standardized procedural education, and better integration of ESD and advanced endoscopy into multidisciplinary tumor boards (MDTs).
This session reinforced a recurring message: personalized medicine, multidisciplinary decision-making, and context-aware practice are often more valuable than rigid adherence to protocol. As the field continues to evolve rapidly, there’s a collective responsibility to ensure that training, reimbursement, and guidelines reflect both clinical reality and emerging innovation.
Live case - with Pradeep Bhandari
Dr. Pradeep Bhandari completed a highly technical ESD case in the rectum, using tunneling and retroflexion strategies. Despite earlier audio issues, the final segment was audible and revealed his emphasis on maintaining control during the final dissection phase, when procedural fatigue and vessel density increase the risk of complications.
He demonstrated careful management of fibrosis and bleeding using real-time injection guidance, particularly underlining how underwater dissection and injection improve both safety and visualization. He also warned against rushing and reminded participants of the importance of patience in the closing stages of complex resections.
Expert Discuttion - Evelien Dekker vs Michael Bourke
The final expert discussion brought together Prof. Thomas Rösch, Prof. Evelien Dekker, Prof. Michael Bourke, and Dr. David Tate in a lively and technically rich debate on the evolution of cold EMR, recurrence prevention, and the use of margin ablation.
Prof. Rösch moderated the session and prompted a review of several clinical cases presented by Bourke, highlighting serrated lesions, dysplasia detection, and real-world dilemmas on whether to ablate margins, close defects, or simply monitor.
Evelien Dekker challenged conventional assumptions about when to resect and when to leave, while David Tate argued the case for context-aware practice, particularly in frail or elderly patients. They also reviewed training challenges, tool selection (e.g., hybrid snares), and the future role of underwater resection in both hot and cold techniques.
The group agreed on one central message: quality resection and strategic personalization of technique matter more than rigid adherence to protocols, especially as endoscopic capabilities continue to evolve.
The event
On June 5th, 2025, the ELUXEO 8000 Experience will bring together leading experts in digestive endoscopy for a scientific event focused on the future of imaging, clinical decision-making, and procedural innovation.
The program includes live cases, structured debates, and high-level discussions moderated by Professors Alessandro Repici and Thomas Rösch. It will offer participants an opportunity to explore current challenges and technological perspectives in endoscopic practice.
To enhance access and continuity, the event will feature support from Mira, an AI-based system designed to assist in the organization and dissemination of scientific content.
Throughout the sessions, Mira will generate a live knowledge log, capturing key points, thematic insights, and relevant contributions. This AI-generated summary will help attendees and remote participants revisit the scientific content in a structured, searchable format.
In addition, a light interaction interface will be available on this page, allowing users to ask Mira questions about the session content in real time.
This is part of an ongoing effort to explore how artificial intelligence can support medical education by enhancing the way knowledge is retained, shared, and applied.